Anabolic Talks

Hey guys, I'm planning a lean bulk cycle and I've been doing some research on a stack of LGD-4033 and MK-677. The idea is that LGD provides the muscle-building component, while MK-677 enhances growth hormone for improved recovery, appetite, and a synergistic effect. Has anyone run a similar stack? What were your results like in terms of mass gain vs. fat gain? What dosages and cycle lengths did you find effective? Also, any side effects to watch out for, especially with water retention or blood sugar from the MK-677?

That's a classic lean bulk stack. The LGD at 5-10mg and MK-677 at 10-25mg is a common starting point. The synergy is definitely there, but you need to be strict with your diet. MK-677 can increase hunger, and if you don't control it, the "lean" part of the bulk goes out the window. Water retention is also a real thing, so keep sodium in check.

From a recovery perspective, the MK-677 is the star here. The improved sleep quality and joint support are invaluable on a heavy bulk. It allows you to train harder and recover faster. Just be mindful of the potential for insulin sensitivity issues with long-term use. A good berberine supplement or similar glucose disposal agent is a wise addition.

I've coached several athletes on this stack. The results for a lean bulk can be impressive if the training and nutrition are dialed in. The biggest mistake people make is not having a proper PCT plan for the LGD. While it's not as suppressive as gear, it will shut you down. Don't skip the blood work to confirm recovery.

Thanks for the feedback. The hunger increase from MK-677 is a good point, I'll be sure to factor that into my meal planning. RecoveryRx, what kind of dosage of berberine do you recommend with the MK-677? And CycleCoach, what does a typical PCT look like for this? A SERM like Nolvadex?

For berberine, 500mg 2-3 times per day with meals is a standard protocol. It helps keep blood sugar stable. As for PCT, CycleCoach is right. A SERM is necessary. Nolvadex or Clomid, depending on suppression levels. Blood work is the only way to know for sure.

I've also had clients stack these, and a key point is managing sleep. While MK-677 helps sleep, some people get lethargic. I recommend taking it before bed. It can also cause vivid dreams, which some find distracting. It's all about listening to your body and adjusting.

Just to add to WellnessWave's point, starting with a lower dose of MK-677 (10mg) and titrating up is a good strategy to manage the side effects like lethargy and hunger. Not everyone needs the full 25mg to get the benefits.

I've seen this combo used by endurance athletes, too, believe it or not. The focus isn't on "bulking" but on recovery and injury prevention. The IGF-1 boost from MK-677 helps with recovery from high-volume training. LGD is less common for them, but some use it for a short burst to build strength without much weight gain.